Check if activation is blocked on that server for the DB

Check if activation is blocked on that server for the DB. The error indicates that

Get-MailboxDatabaseCopyStatus  MBX-DB1\EMAIL2 |FL activationsuspended

or for the entire server

Get-MailboxServer  EMAIL2 | FL DatabaseCopyAutoActivationPolicy

If you want to remove that block:

Get-MailboxDatabaseCopyStatus  MBX-DB1\EMAIL2 |  Resume-MailboxDatabaseCopy